HomeIndustriesProductsServicesPartnersAbout Us

Customer Login

Home arrow CFD Paper Library arrow Software Tool arrow CFD-VIEW arrow Modeling of Microfabricated Microneedles for Minimally Invasive Drug Delivery, Sampling and Analysis
Modeling of Microfabricated Microneedles for Minimally Invasive Drug Delivery, Sampling and Analysis
AT A GLANCE
Software Tool
Physics Used
Industry Area
Request Paper
Authors
D. Trebotich, J.D. Zahn and D. Liepmann University of California, Berkeley B. Prabhakarpandian CFD Research Corp.
Abstract
We compare simulation to analysis and experiments for flows in three microneedle geometries - straight, bent and filtered. The bent microneedle was found to have the highest fluid carrying capacity of 0.082 ml/sec at 138 kPa with a Reynolds number of 738. A microneedle with a built in microfilter had a flow rate of 0.07 ml/sec. Although the throughput of these microneedles is low they compare favorably with other microneedle designs. Laminar flow models were found to accurately predict the flow behavior through the microneedles. All computational modeling was performed with CFDRC CFD-ACE+ suite of software tools.
Keywords
microneedles, microfluidics, computational model
Source
Biomedical Microdevices 5:3, 245-251, 2003
Reviews
© 2012 ESI Group CFD Portal