A multidisciplinary computational investigation has been conducted to examine the feasibility of controlling the buffet problem using different active flow control methods.  Tangential central blowing (TCB), tangential vortex blowing (TVB), and tangential spanwise blowing (TSB) methods were used to inject high-momentum fluid into the vortical flow of generic fighter aircraft flying at 30° angle of attack.  The effect of blowing strength on the buffet responses is also investigated.  The injection is aimed to strengthen the wing vortices and to delay the onset of breakdown in order to alleviate the twin-tail buffet.  The results indicated that blowing directly into the core of the leading-edge vortices has more potential in controlling the buffet responses and in the reformation of unburst vortices with larger length.  The TVB method produced the most favorable results with a reduction of about 43% in the buffet excitation parameter and a redution of about 40% in the amplitude of bending deflection.  This multidisciplinary investigation is conducted using the multidisciplinary computing environment (MDICE).