The development of an active micromixer using PZT-generated vibration for DNA purification and sequencing reaction clean-up is presented. The flow patterns inside the mixing chamber were visualized using fluorescent beads. A figure-eight flow pattern was discovered. The flow patterns observed demonstrated an apparent correlation to the vibrational mode shapes expected for the exciting thin PZT actuated silicon membrane. A model of a circular fixed plate was created for modal analysis using CFD-ACE+. Preliminary analysis was performed and is presented for free vibrations of the membrane in the absence of fluidic loading.